acrisorcin
- Product Name
- acrisorcin
- CAS No.
- 7527-91-5
- Chemical Name
- acrisorcin
- Synonyms
- Akrinol;acrisorcin;Acrisorcina;acrisorcin USP/EP/BP;acridin-9-amine,4-hexylbenzene-1,3-diol;Bis(9-aminoacridinium)salz des hexylresorcine
- CBNumber
- CB9935518
- Molecular Formula
- C13H10N2.C12H18O2
- Formula Weight
- 388.508
- MOL File
- 7527-91-5.mol
acrisorcin Property
- Melting point:
- 189-190 °C
acrisorcin Chemical Properties,Usage,Production
Originator
Aminacrine hexylresorcinate ,ZYF Pharm
Uses
Antifungal.
Manufacturing Process
4-Hexylresorcinol 194.0 g is added to a solution composed of 56.1 g potassium hydroxide in 1.5 L of water with stirring, and the mixture heated to about 40°C to effect complete solution. The pH of this solution is 12. A second solution of 9-aminoacridine hydrochloride is prepared as follows: 2 L of water containing 83 ml of concentrated hydrochloric acid are heated with stirring to about 80°C. Slowly 194.0 g of 9-aminoacridine are added. Heating is continued until a clear solution is obtained. About 2 ml of additional concentrated hydrochloric acid are added in small increments until the solution is slightly acid (pH of about 6). The 4-hexyl resorcinol solution is now slowly added under rapid agitation to the 9-aminoacridine hydrochloride solution. A copious precipitate is formed which, upon :stirring and continued addition of the 4-hexylresorcinol solution, becomes a creamy yellow slurry. At the end of the addition, the pH is 7-8 (indicator paper). The slurry is stirred while heated for an additional 15 min and then rapidly filtered on a 15 cm Buchner funnel. The product thus obtained is washed thoroughly, using about 1 L of cold water, to give a very pale yellow color in the last wash. The compound is then pressed dry and then oven-dried for 2-3 h at 50°C. The resultant product, 9- aminoacridine 4-hexyl resorcinolate, has a melting point of 189°-190°C.
brand name
Akrinol (Schering).
Therapeutic Function
Antifungal, Anthelmintic
acrisorcin Preparation Products And Raw materials
Raw materials
Preparation Products
acrisorcin Suppliers
View Lastest Price from acrisorcin manufacturers
- Product
- acrisorcin 7527-91-5
- Price
- US $0.01-1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 50 tons
- Release date
- 2020-05-12
- Product
- acrisorcin 7527-91-5
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.9%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-07-19